Antihistamines and Adjunctive Symptom Relief Antihistamines are frequently used as an adjunctive, or supplementary, treatment for Canine Atopic Dermatitis, though their efficacy as a sole therapy is generally considered low compared to newer, more targeted agents. First-generation antihistamines, such as diphenhydramine and hydroxyzine, are sometimes employed due to their mild sedative effect, which can help break the cycle of scratching...
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