Oncology Applications: FISH for Cancer Diagnosis and Prognosis The primary and largest application area for the Fluorescence In Situ Hybridization Probe is in oncology, where it is used to diagnose, classify, and determine the prognosis of various cancers, most notably hematological malignancies and solid tumors. FISH is instrumental in detecting hallmark genetic changes in cancer cells, such as gene amplifications, deletions, and specific chromosomal...
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