Xeno-Free Culture Techniques Minimizing Immunogenicity Risk 2026 The use of animal-derived components, such as bovine serum, in the propagation of human cell lines poses two significant risks: the transmission of zoonotic pathogens and the introduction of non-human antigens, which can trigger an adverse immune response in patients. Xeno-Free Culture techniques, centered on the use of human-derived supplements like HPL, are now mandatory for therapeutic...