For patients suffering from chronic, non-infectious uveitis, particularly those with disease in both eyes (bilateral disease) or inflammation in the back of the eye (posterior uveitis), combination therapy is the necessary standard of care. This approach involves simultaneously using two or more different classes of agents to attack the inflammation through various mechanisms and delivery...
In early 2026, the emergence of oral Janus kinase inhibitors like brepocitinib and filgotinib is providing a major breakthrough for patients who prefer systemic oral therapy over frequent intraocular injections. These 2026 small-molecule inhibitors work by blocking the JAK and TYK2 signaling pathways, effectively suppressing a broad range of pro-inflammatory cytokines that contribute to macular...
A major evolution in the treatment of chronic and severe non-infectious uveitis is the increasing adoption of biologics, which offer a targeted approach to immune system modulation. These sophisticated therapies, often monoclonal antibodies like adalimumab (an anti-TNF agent), specifically target inflammatory pathways, such as tumor necrosis factor-alpha (TNF-α), that drive the disease....
The long-term projections for the Uveitis Drug Market point toward sustained expansion in the United States as treatment paradigms shift and diagnosed patient populations grow. For comprehensive projections, consult the Uveitis Drug Market Projections.
U.S. growth will be fueled by multiple converging trends: expanded diagnosis through improved imaging and referral networks, increased uptake...
A defining 2026 trend in ocular immunology is the transition toward oral TYK2/JAK1 inhibitors as a systemic alternative to traditional steroids. In 2026, the clinical community is closely watching the rollout of brepocitinib, which received Fast Track Designation and has shown promising Phase II results in reducing inflammation for "non-anterior" uveitis. Unlike broad-spectrum...
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